Namco Museum DS allows gamers to experience a virtual arcade portal where they can choose from up to seven classic games: Pac-Man, Galaga, Xevious, Dig Dug II, Galaxian, Mappy, and The Tower of Druaga. Also featured is Pac-Man VS. -- Originally released in 2003 – For the first time in Pac-Man history, you and your friends now have the chance to be the famous ghosts from Pac-Man! With one person playing as Pac-Man and up to 3 people playing as ghosts, this incredibly fun multiplayer game offers nonstop enjoyment with just one game card.

Players can use the screen mode selection which allows the use of different screen combinations on the Nintendo DS. Players can also enjoy wireless battles in Pac-Man VS, which features downloadable play and four players can battle using only one Game Card.